Buccaneers vs Lions Prediction, Betting Odds, and Best Bet for Monday Night Showdown


Tampa Bay Buccaneers vs Detroit Lions Game Details | |
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Date | Monday, October 20, 2025 |
Time | 7:00 pm ET / 4:00 pm PT |
Venue | Ford Field, Detroit, MI |
Broadcast | ABC and ESPN |
The NFC’s top seed and the league’s most resilient team square off tonight for game 1 of the MNF double header when the Tampa Bay Buccaneers, who are 5-1, visit the Detroit Lions, sitting at 4-2 at Ford Field. This isn’t just a battle between division leaders, instead, it’s a playoff-caliber test between 2 teams with very different vibes. Tampa Bay is surging, while Detroit is regrouping after a punch to the mouth in their KC matchup last week.
Game Details and Betting Odds
Kickoff is set for 8:15 p.m. ET, and it’s a game with real implications for the NFC playoff picture. Detroit opens as an 8-point favorite, with the over/under set at 53.5 points. The Lions are -285 on the moneyline, while the Buccaneers are listed at +230, making Tampa a solid value bet for upset hunters.
Team | Spread | Total | Moneyline |
---|---|---|---|
Buccaneers | +8 −110 |
O 53.5 −108 |
+230 |
Lions | −8 −110 |
U 53.5 −112 |
−285 |
We feel that the spread is a little rich considering how these 2 teams have been trending. Tampa has won 3 straight games, which includes a 30-19 beatdown of the 49ers last week, while Detroit just suffered its second loss of the season in a flat showing at Kansas City. The bookmakers are obviously leaning heavily to Detroit’s homefield advantage, but will that be enough against a surging Bucs team?
Tampa’s Confidence Meets Detroit’s Resolve
If there’s one thing Dan Campbell’s team has done well over the past few seasons, it’s bounce back.
The Lions have not lost consecutive regular-season games since October 2022, which is just incredible over a run of 50 games. But that streak is now in jeopardy on the MNF stage. Detroit’s secondary is absolutely decimated, with safety Brian Branch suspended, and 5 DBs on the IR. Starters Kerby Joseph, Avonte Maddox, and rookie Terrion Arnold all missed practice this week and are listed as out.
That’s not great when you’re facing a QB who’s in a solid rhythm like Baker Mayfield. Mayfield has quietly put together a 1,539-yard, 12-TD season, with just a single pick. He’s top-10 in QBR at 108.5 and has had excellent command of the offense. His top target, Emeka Egbuka, has 469 yards and 5 touchdowns of his own. And even though the Bucs have been without Mike Evans for the past 3 games, he may return tonight as he’s still listed as questionable and even practiced on Saturday.
Tampa’s offense ranks 6th in points per game with 27.5 and is averaging 365.8 YPG. Their success starts with their passing attack, which is 8th in the league and hardly ever turns the ball over. They don’t run often or particularly well as they have just 109.3 rushing yards per game — but Rachaad White has stepped up in a big way with 3 rushing touchdowns over the past 2 games.
On the defensive side of things, Tampa’s front 4 is heating up. They had 6 sacks last week and now have 16 on the year, which is 5th best in the NFL. Yaya Diaby leads the team with 3 sacks, while Vita Vea continues to cause absolute chaos inside. Vea pressured 49ers QB Mac Jones on nearly 70% of dropbacks despite constant double-teams. That allowed the Bucs to get pressure in the pocket without blitzing, which is a major asset when facing a quarterback like Jared Goff, who thrives with a clean pocket.
Detroit’s Wounded Secondary Faces Major Test
The Lions undoubtedly still boast one of the league’s best all-around offenses. Jared Goff has been incredibly efficient, completing 75.9% of his passes for 1,390 yards and 14 TDs to just 2 interceptions. His connection with Amon-Ra St. Brown is the heartbeat of this offense. St. Brown has 44 catches, 452 yards, and 6 touchdowns.
Detroit also leans on a solid backfield duo. Jahmyr Gibbs has rushed for 390 yards, and David Montgomery adds another 334 yards and 4 rushing scores. Together, they power a ground game that puts up a monstrous 128.7 YPG, which is a top-10 line..
But the defense is where things get tricky. The Lions allow 23.7 PPG, which places them 20th in the league, and have struggled against explosive plays. They’ve allowed 308.2 total yards per game, which looks decent on paper, but that number doesn’t account for red zone lapses and injuries. And now, with their top safety out and key corners hurt, this secondary is walking a tightrope.
Another concern we’re seeing is that Detroit doesn’t force turnovers. They’ve only managed 6 interceptions all season, and that’s a problem when you’re facing a quarterback who protects the ball as well as Mayfield does.
Why the Bucs Can Pull Off the Upset
Look past the records and the public perception. The Buccaneers have won 5 of their first 6 games, and that includes recent wins over the Seahawks and 49ers. These teams have elite defenses or dynamic playmakers, and Tampa handled them.
Detroit, meanwhile, has beaten up on teams like Chicago, Cleveland, and Baltimore early in the year, but their loss to Kansas City exposed some real holes, particularly in their ability to adjust in-game and protect Goff under pressure.
Tampa Bay ranks 9th in time of possession, keeping its defense fresh for most of the game. They’re 12th in 3rd-down conversions and efficient in the red zone. That combination makes them a total nightmare for teams with injured secondaries and limited pass rush depth — both of which describe Detroit perfectly right now.
Baker Mayfield is simply playing smarter football, the Bucs’ defensive front is thriving, and they’ve proven they can win in tough spots. Add in the possibility of Mike Evans returning, which only adds to the repertoire, and Tampa Bay looks like a team with serious upset potential.
Prediction and Best Bet
This line feels too wide, and we think the bookmakers are missing the mark. That’s what makes this bet great. Detroit’s injuries in the secondary are a real concern, and Tampa Bay is one of the hottest teams in football. Unless the Lions find a way to slow Mayfield without blitzing, and unless Goff can stay upright under pressure, this could get uncomfortable fast.
- Prediction: Buccaneers 23, Lions 17
- Best Bet: Tampa Bay Buccaneers +8 on the Spread
This is too many points to give a 5-1 team with a red-hot QB and a defense that just posted 6 sacks. If you’re feeling really bold about this game, sprinkle the moneyline at +230, but that’s still a tall order given how deep the Detroit roster is.

Matt Brown
Head of Sports Betting and DFS
Matt’s love for sports betting and daily fantasy sports, coupled with a deep understanding of football, hockey, and baseball, shapes his innovative thoughts on Hello Rookie. He has a B.S. in Aeronautical Computer Science and a M.S. in Project Management.