Categories: NFL

San Francisco at Seattle Betting Preview: Best Bet for Thursday Night Football

We are back for some revenge from last Thursday night that saw the Falcons beat the Bucs in wild fashion. We have had some decent Thursday night matchups through the first 5 weeks, and I think we will have another good game this week!

The 49ers roll into Seattle with a 2-3 (.400) record, coming off an embarrassing loss where they were up 13 in the 2nd half. Seattle sits at the top of the NFC West for now at 3-2 (.600) and looks to build on the 49ers struggles!

Purdy and 49ers Own This Matchup

It’s pretty simple, the 49ers own this matchup, and the Seahawks injuries have caught up to them. I believe the 49ers bounce back and don’t lose to all 3 division teams to start off. They have lost to both the Rams and the Cardinals; it would be a headline if they lost to Seattle to start 0-3 in the division.

The 49ers were up 13 in the 2nd half vs Cardinals and blew that game. This is a good spot for what is still one of the better rosters and coached teams in the NFL. Brock Purdy moved the ball vs Cardinals, and I think his completion % improves vs this Seahawks defense while limiting the turnovers.

In 3 games vs Seattle, Purdy is 3-0 with an average passer rating of 109, a 69% completion %, 264 avg passing yards and 5 total TDs to 2 INTs. While two of those games were at Seattle. Purdy has been good so far this season with a 95.3 passer rating while completing 66% of his passes. His turnover rate must improve, and I believe it will here.

Another big contributor to this offense has been Jordan Mason who is averaging 107 rushing yards per game through 5 games. Seattle has allowed the 12th most rushing yards, 8th most rushing yards per attempts, and I expect him and George Kittle to do some damage this week.

Thursday Night Trends

If you are a trend follower, I have a couple nice trends for Thursday night games to back this pick. On Thursday night divisional matchups, divisional home dogs of 3 to 9.5 points with .400 win% or better, are 0-10-2 ATS since 2012. Seattle is currently a home dog of +3.5 with a .600-win percentage.

Also on Thursday night matchups, the away favorite with a losing record vs a home dog with winning record is 12-3-1 ATS since 2011. The 49ers are 2-3 as a road favorite, while Seattle is 3-2 as home dogs. The books clearly see the 49ers as a better team giving them -3.5 on the road in a short week and I think it’s the right side.

Best Bet: 49ers -3 (-114) Bet365

Wade Reeser

Wade Reeser provides winning sports information to a wide variety of customers through his handicapping service, Proven Wagers! Just how good are these guys? They're currently up over 600 units since 2023. They can be found on X @ProvenWagers

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