Best NFL DFS Picks Today: Top Value Plays for Sunday’s Slate

Sunday’s NFL DFS main slate is loaded with 11 games kicking off between 1 p.m. and 4:25 p.m. ET, but one matchup is impossible to ignore: Jahmyr Gibbs and the Lions traveling to face a reeling Cardinals defense in a game with a 54.5-point over/under, the highest total on the board by a wide margin. That shootout environment is going to pull heavy DFS attention from both sides, and it’s where a lot of today’s best value lives.

Beyond the Lions-Cardinals game, we’re targeting a mix of proven volume plays and situational value created by injuries elsewhere on the slate. Here are five picks worth building around for cash games and GPP lineups on DraftKings and FanDuel today.

Jared Goff, QB — Detroit Lions at Arizona Cardinals ($8,100 FD)

Goff is squarely in play for Sunday NFL DFS lineups given the context of this matchup. Arizona’s defense has been one of the most exploitable units in the league through the air, and Detroit’s offense is humming with Amon-Ra St. Brown, Jameson Williams and Jahmyr Gibbs all drawing consistent volume. The Cardinals-Lions total sits at 54.5, by far the richest game environment on the Sunday slate, and that kind of number signals both offenses are expected to move the ball freely.

Detroit leans on 11 personnel on roughly 64% of its offensive snaps, among the highest rates in the NFL, which keeps St. Brown, Williams and Isaac TeSlaa on the field together and gives Goff a deep, reliable group of options to throw to. In a game projected to be the highest-scoring on the board, Goff offers both a high floor and real ceiling for DraftKings lineup and FanDuel picks builders looking to pay up at the position.

D’Andre Swift, RB — Chicago Bears at Green Bay Packers ($6,200 DK / $6,500 FD)

Swift is in line for a workload bump after the Bears ruled out Kyle Monangai (toe) for Sunday’s game against Green Bay. Monangai had taken over as Chicago’s early-down banger last week, rushing 30 times for 146 yards and two touchdowns, but that path is now cleared for Swift to reclaim the lead role. He was a full practice participant on Friday without an injury designation, signaling he’s ready to handle a full workload.

The matchup plays right into his hands. Green Bay ranks near the bottom of the league in run defense efficiency, and Swift has handled at least 15 carries and 17 total touches in every outing when he’s been the clear lead back this season. He also remains Chicago’s primary pass-catching back out of the backfield, with 12 targets on the season compared to five for Monangai, giving him a reliable floor through receptions even if the Bears fall behind. At $6,200 on DraftKings, that’s strong NFL DFS value for a player projected to see 20-plus touches — if you’re new to the platform, a DraftKings promo code can help offset some of your entry fees while you build this lineup.

Trey McBride, TE — Arizona Cardinals vs. Detroit Lions ($6,700 DK / $7,200 FD)

McBride is the clear chalk play at tight end today, and for good reason. He’s recorded at least seven catches in all four games this season and leads all tight ends with 33 receptions, racking up more than 240 receiving yards already. The matchup only sweetens the pot — Detroit has allowed the most catches (37) and a league-high six touchdowns to tight ends this season, making this one of the most favorable individual matchups anywhere on the slate.

With the Cardinals likely playing from behind in a shootout against Detroit’s high-powered offense, Arizona’s passing volume should spike, and McBride is quarterback Jacoby Brissett’s clear top target. He’ll carry heavy ownership in both cash games and GPP lineups today, but the volume and matchup both justify paying up. This is as close to a lock as the DFS player pool offers this week.

Michael Wilson, WR — Arizona Cardinals vs. Detroit Lions ($6,400 DK)

Wilson has emerged as one of the Cardinals’ top two options in the passing game alongside McBride, and he’s in an excellent spot to capitalize on Detroit’s leaky pass defense. With the Lions-Cardinals total sitting at 54.5, Arizona’s implied team total of around 24.5 points still leaves plenty of room for Wilson to produce in what should be a pass-heavy script if Arizona trails.

Brissett has leaned on Wilson and McBride as his top two weapons through the air, and that two-man connection gives Wilson a legitimate role even with rookie Marvin Harrison Jr. working his way back into the mix. At $6,400, Wilson represents a strong mid-range NFL DFS picks option for lineups that are already paying up at running back or quarterback elsewhere on the board.

Isaac TeSlaa, WR — Detroit Lions at Arizona Cardinals ($3,400 DK)

TeSlaa is the value flex of the day, and the recent trend lines are hard to ignore. He’s coming off his best game of the season, catching four of eight targets for 95 yards against Carolina, and the week before he hauled in three catches for 66 yards against the Jets. Those two performances account for 161 of his 187 receiving yards in 2026, and his 20.8 yards-per-catch average ranks among the best in the league for any receiver with a meaningful snap share.

Detroit’s heavy use of three-receiver sets keeps TeSlaa on the field alongside St. Brown and Williams, and he now draws a Cardinals secondary that’s been one of the most beatable units in the NFL through the air this season. At just $3,400, TeSlaa offers real salary-saving upside that can free up cap space to pay up at running back or tight end elsewhere in your DraftKings lineup.

Building Your Lineup

The Lions-Cardinals game is the engine room of today’s slate, and stacking pieces from that matchup — Goff, Gibbs, McBride, Wilson and TeSlaa in various combinations — is a reasonable way to attack both cash games and GPP builds given the inflated point total. Just be mindful that heavy ownership on that game could cap your ceiling in large-field tournaments, so pairing one or two Lions-Cardinals pieces with a contrarian angle like Swift in the Bears-Packers game can help differentiate your roster.

From a salary-cap standpoint, TeSlaa’s rock-bottom price tag is the kind of player that makes expensive studs like Goff or McBride affordable on the same roster. If you’re building multiple lineups today, consider pivoting off the popular Cardinals stacks in a portion of your builds, since public DFS players tend to flock toward the highest-total game on the board. A balanced approach — one premium play, a couple of proven mid-range options and a true value piece like TeSlaa — gives you a real shot at cashing while still leaving room for tournament upside. For bettors also looking to play the matchups straight up, checking the latest NFL odds alongside your DFS research never hurts.