Colts vs. Jaguars: Betting Odds, Predictions, and Best Bet for Sunday, October 6

Week 5 of the NFL season includes an AFC South rivalry between the Colts and the Jaguars. Will Jacksonville finally get its first win? How healthy are the Colts?

We’ll answer those questions and more. Dive into our betting preview for all of the info you need to know. This should be a good one! Best of luck with all of your Week 5 wagers.

Status of Anthony Richardson & Jonathan Taylor?

The Colts pulled off a nice upset at home last week against the Steelers, but they endured some unfortunate injury luck. Starting QB Anthony Richardson had to leave the game with an oblique strain, and his status is up in the air for Sunday. Starting RB Jonathan Taylor is also listed as questionable with an ankle sprain.

At the time of this writing, it looks like Richardson is more likely to suit up than Taylor. Richardson practiced in a limited capacity on Wednesday, but Taylor was unable to get any reps in. Indy’s offense has averaged 6.1 yards per play this season (5th), but you have to wonder how they’ll perform without one or both of their superstars.

On the flip side, the Indy defense has been kind of underwhelming. The Colts rank just 15th in yards per rush allowed and an ugly 26th in yards per pass allowed. Look for Trevor Lawrence to try to exploit this vulnerable secondary.

Will the Jaguars Finally Get Right?

Jacksonville is still winless at 0-4 and this is a ‘put up or shut up’ game for them. There seems to be some inner rumblings between head coach Doug Pederson and the players. That said, the Jags did hang tough with the Texans last week, much to the delight of their point spread backers.

The strength of the Jacksonville offense so far in 2024 has been its running game. The Jags are averaging 5.7 yards per carry behind Tank Bigsby and Travis Etienne. Those two backs should find some success against an Indy d-line that will be without Tyquan Lewis and possibly without Kwity Paye.

The Jacksonville defense has done a remarkable job of stopping the run this season, as they rank 6th in yards per rush allowed. Their secondary has been awful though, as they’re giving up 8 yards per pass (30th). They’ve also yet to generate any type of consistent pass rush.

Best Bet: Jaguars -2.5 (-120)

I’m going to go a little contrarian with this pick, so give me a minute to explain. Why is a winless team laying basically a full field goal in this spot against a squad that’s 2-2? It’s almost like the books are begging for Colts action on this game.

This is a fantastic opportunity to buy low on the Jags after their 0-4 start. It’s also a good spot to sell the Colts at a high after their big upset win over the Steelers last week. Also, I like that the Jags should be getting some key pieces back for this game.

The offense hasn’t looked great, but getting Evan Engram and Gabe Davis back will do wonders for Trevor Lawrence’s confidence. Both Engram and Davis were able to practice in a limited capacity on Wednesday. Let’s lay the small number and watch the Jags get their first W of the year!