Monday Night Football brings an NFC East grudge match to Lincoln Financial Field, where the 2-4 Dallas Cowboys visit the 2-4 Philadelphia Eagles at 8:15 p.m. ET. With Jalen Hurts sidelined, Tanner McKee running a thin Philadelphia passing game, and Dallas leading the league in pass rate, this game script leans hard toward the Cowboys through the air. The weather impact rates Low, with about 58 degrees at kickoff, a light 5 mph breeze and a 0% chance of rain, so conditions will not get in the way of anyone’s lineup.

Single-game slates are a different animal than a full Sunday main slate. Salaries are tight, ownership clusters around a handful of names, and one touchdown swings everything. Here are the five NFL DFS picks we like for Monday Night Football DFS, with salary context from DraftKings Showdown (where the cap is $50,000) and FanDuel pick context mixed in. All pricing comes from pre-inactives numbers, so confirm final statuses before lock.

CeeDee Lamb, WR – Cowboys ($11,000 DK FLEX)

Lamb is the most expensive player on the board and still the cleanest ceiling play. He leads the NFL with 69 targets, turning them into 48 catches, 577 yards and four touchdowns. He also torched Houston for 189 yards on 17 receptions in a recent game.

The matchup is friendly. Dallas throws on roughly 68% of its first-and-ten plays, the run game is nearly nonexistent, and the Eagles are working without Nolan Smith, with edge rushers Jonathan Greenard and Jalyx Hunt listed as questionable. His range is wide, so he is more of a ceiling bet than a safe floor, but at the top of a Monday Night Football DFS pool he is the first name on the list.

Dak Prescott, QB – Cowboys ($10,400 DK FLEX)

Prescott has completed 163 of 246 passes (66.3%) for 1,639 yards, 10 touchdowns and five interceptions, and his 87 first downs lead the league. He has put up double-digit fantasy points in every game this season. The last two weeks have been rougher, with four interceptions, and he completed just 52.6% against blitzes in those losses.

The bounce-back case is simple. Philadelphia defensive coordinator Vic Fangio has blitzed on only 24.1% of dropbacks, and the Eagles’ pass rush is shorthanded. Dallas also has almost no ground game, so the offense runs through Prescott’s arm. In a DraftKings lineup, he is the natural anchor for a Cowboys stack.

George Pickens, WR – Cowboys ($9,000 DK FLEX)

Pickens is the discount version of Lamb. He sits second on the team with 52 targets, 33 receptions and 428 yards, though he has just one touchdown so far. That low touchdown total is the reason to be interested: the volume is there, and positive regression is the kind of thing that shows up on a night when Dallas is expected to throw it 50-plus times.

At $9,000 he costs $2,000 less than Lamb, which opens room to fit a pricey running back or a second Eagles piece. Dallas has also allowed 11 passing touchdowns and a 110.2 opposing passer rating on defense, which tells you the game could turn into a shootout if Philadelphia can move the ball at all. For MNF value plays, Pickens is the one we would lean on in a hedge against Lamb being heavily rostered.

Dallas Goedert, TE – Eagles ($6,400 DK FLEX)

With DeVonta Smith and Dontayvion Wicks both out, McKee is short on weapons, and Goedert is the most trusted of the bunch. Since returning two weeks ago, he has played 69% and 81% of the snaps, seeing nine and eight targets and catching six passes in each game. The yardage has been modest at 38 and 61, and he has not yet had a red-zone look, but the target share is real.

Dallas has been burned by short completions, with opponents connecting on 83.6% of throws traveling 10 air yards or fewer. That is exactly where McKee and Goedert live. He is listed as cleared, and he is our pick for the best mid-priced option on the Philadelphia side.

Saquon Barkley, RB – Eagles ($9,600 DK FLEX)

Barkley is the swing player of the slate. He is questionable with a hamstring issue and has not played since Week 4, but he has been logging full practices and is expected to return. In his four games he has 36 carries for 182 yards, a 5.0 yards-per-carry average. The matchup could hardly be better, as Dallas allows 4.7 yards per carry and 149.8 rushing yards per game, along with seven rushing touchdowns.

The risk is workload and stamina after the layoff, and Dameon Pierce is the next man up if Barkley is limited or out. Check the inactives before lock. If Barkley is active, he is a strong piece, and if he is not, Pierce becomes a thin but cheap pivot, and Goedert’s value goes up even more. For those who want a flexible approach, a look at our live NFL odds page can help you gauge how the market is reading this game.

Building Your Lineup

The simplest approach is a Cowboys-heavy build: Prescott with Lamb or Pickens, since all of Dallas’s offense runs through the pass game. Pairing Prescott with both receivers is expensive but would take advantage of Dallas’s league-high pass rate. On the Eagles side, Goedert is the best value, and Barkley is the high-upside bet if he is cleared to play.

Because ownership will cluster on Prescott and Lamb, consider pivoting captain slots toward Pickens or Barkley to separate from the field. If you play on DraftKings, remember captain pricing is 1.5 times FLEX, so a $9,000 Pickens costs $13,500 at captain, while Lamb costs $16,500. If you are new to daily fantasy and want to try other contest formats, our PrizePicks review is a good starting point. Whatever you build, lock in after final inactives and play within your budget.