Best MLB DFS Picks Today: Top Value Plays for Friday, June 12

Friday night brings one of the better MLB slates of the week, with a full card of 12-plus games locking into DraftKings and FanDuel starting around 7:05 PM ET. The headliner is Jacob Misiorowski taking the mound for Milwaukee, giving this slate an elite SP anchor that does not come along every night. Throw in deep bats across several favorable matchups and you have got the ingredients for a big DFS evening whether you are playing cash games or GPP tournaments.

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Today’s approach centers on locking in SP value at the top of the slate and riding the Atlanta Braves offense in a favorable road spot. The Braves are baseball’s best team at 45-23, and they are catching a Mets starter with leaky recent form. On the pitching side, we are targeting two arms with significant strikeout upside who should eat innings and pile up fantasy points across both platforms.

Jacob Misiorowski, SP — Milwaukee Brewers ($12,000 DK)

There is no getting around it: Misiorowski is the most dominant pitcher in baseball right now, and he is the unquestioned top priority on today’s DraftKings lineup. The Milwaukee righty entered June with a 12-5 record and a 2.81 ERA, having already racked up more than 200 strikeouts — a pace that has scouts and DFS analysts alike running out of superlatives. His start on June 6 against Colorado showcased exactly why he is worth every penny of a $12,000 salary: he hit 103.7 mph on the radar gun, setting a new record for the fastest pitch by a starting pitcher since pitch tracking began in 2008.

Tonight Misiorowski faces Philadelphia at American Family Field, and while the Phillies have talent, any lineup stepping into the box against that kind of pure velocity and elite spin rate is in trouble. His strikeout ceiling is among the highest on the slate — he has been posting double-digit K games regularly, including eight strikeouts across seven shutout innings in a recent start. He also reached the 100-strikeout mark earlier than any other pitcher in the league this season. At $12,000, he is the most expensive SP on the board, but the per-dollar production justifies the spend. If you are building a lineup that needs differentiation in GPP formats, Misiorowski paired with a Brewers mini-stack is one of the highest-upside constructions you can put together tonight.

Joe Ryan, SP — Minnesota Twins ($10,000 DK)

Ryan has quietly become one of the most consistent fantasy starters in the American League, and his June 12 home start against St. Louis deserves your full attention. Through 13 starts in 2026, the Twins righty carries a 3.07 ERA and 84 strikeouts across 76.1 innings. Five of his last six outings have been quality starts, and he has posted a 2.39 ERA with a 0.93 WHIP across that stretch. He has also struck out exactly nine batters in each of his last three consecutive outings, a streak that signals outstanding current-form command and stuff.

Target Field in Minneapolis plays as a modest pitcher-friendly environment, and the Cardinals carry one of the more exploitable offenses in the National League tonight. At $10,000 on DraftKings — a full $2,000 cheaper than Misiorowski — Ryan represents the quintessential value-play pitcher: near-ace production at a salary discount. If you are not paying up for Misiorowski as your primary SP, Ryan is the obvious pivot. If you are going with both pitchers in the same lineup, Ryan at $10,000 is what makes that build work from a salary-cap standpoint.

Matt Olson, 1B — Atlanta Braves (~$5,300 DK / ~$4,200 FD)

The Braves have been baseball’s most dominant team this season, and tonight they travel to Citi Field to face the New York Mets with Nolan McLean on the mound for New York. McLean’s ERA sits at 3.98, but his recent results paint a bleaker picture — he has gone just 3-7 in his last ten decisions, suggesting the underlying regression is already happening. That makes the Braves’ left-handed power bats a high-priority stack target on both DraftKings and FanDuel tonight.

Olson is the centerpiece of that stack. He is slashing .272/.344/.558 with 19 home runs and 50 RBIs through the season’s first half, putting him on pace for one of the better offensive campaigns of his career. He is a left-handed hitter going against a right-handed starter who has been consistently beaten, and Citi Field plays fair for power hitters who elevate the ball. In a slate full of quality bats, Olson stands out as a near-lock for cash game lineups. His .558 slugging percentage ranks in the top ten among all qualifying first basemen in the National League.

Michael Harris II, CF — Atlanta Braves (~$4,400 DK / ~$3,500 FD)

If you are stacking the Braves tonight — and you should be — Harris II is the complementary piece that makes the stack worth playing. The 25-year-old center fielder has been outstanding in 2026, posting a .306 batting average with 13 home runs and 40 RBIs while carrying a .513 slugging percentage. Those are all-star caliber numbers at a price point that still allows you to spend heavily at other positions in your lineup.

Harris II is a multi-category threat with both speed and power, and he hits in the middle of one of baseball’s most productive lineups. He has recorded 71 hits across 232 at-bats this season, and his 31 runs scored reflect how often he gets on base and gets driven in by the deep Braves order. His pricing relative to his production makes him one of the stronger salary plays on any DraftKings slate he appears on. Pairing him with Olson in a two-man Braves stack versus McLean is one of the highest-floor, high-ceiling constructions available tonight without breaking the salary cap.

Shohei Ohtani, OF — Los Angeles Dodgers (~$8,800 DK / ~$6,400 FD)

The Dodgers travel to Chicago to face the White Sox tonight, with Sean Burke getting the start for Chicago. Burke carries a 3-3 record and a 3.88 ERA, but his 1.45 WHIP is a significant red flag — he is putting far too many runners on base for an elite Dodgers lineup to ignore. Los Angeles leads the NL West and ranks among the better offenses in the league, and Ohtani batting at .299 for the season is precisely the kind of elite bat you want against a pitcher who consistently works into trouble via baserunners.

Ohtani’s combination of elite contact, plus power, and stolen base upside makes him one of the most reliable floor-plus-ceiling plays in all of DFS on any given night. Tonight, with Burke on the mound and the Dodgers installed as road favorites, Ohtani is a strong anchor for the outfield in any lineup construction. His career numbers against pitchers with elevated WHIP rates are devastating, and Burke’s 1.45 WHIP this season puts him squarely in the category of arms Ohtani feasts on. He is expensive, but he is worth the salary investment in both cash games and GPP contests.

Building Your Lineup

The cleanest construction on tonight’s slate involves locking in Misiorowski at SP1, stacking the Braves with Olson and Harris II, and anchoring the outfield with Ohtani. Joe Ryan can serve as your SP2 if you want to double-stack the pitching and take a zero at one other spot — that combination gives you strikeout upside from two elite starters alongside a live Braves stack against a vulnerable arm and Ohtani’s premium matchup against an over-walking Chicago starter.

For GPP tournaments, adding a third Brave — Ozzie Albies or Mauricio Dubon at a lower price point — could unlock a tournament-winning score if Atlanta explodes against McLean early in the game. In cash games, the Olson and Harris II tandem provides enough Braves exposure without overloading the roster. Monitor the confirmed lineup reports before lineups lock, watch for any late-breaking injury news out of Atlanta, and check ownership percentages as the night approaches. Misiorowski figures to be highly owned given his dominance, but his production is too consistent to consider fading in any format. Build around him and let the strikeouts do the work.